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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPCN2
All Species:
5.76
Human Site:
S406
Identified Species:
12.67
UniProt:
Q8NHX9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHX9
NP_620714.2
752
85243
S406
L
F
N
E
L
D
R
S
V
V
K
E
H
P
P
Chimpanzee
Pan troglodytes
XP_001173935
763
85554
V417
N
W
I
F
W
S
R
V
F
L
A
Q
H
P
P
Rhesus Macaque
Macaca mulatta
XP_001101571
752
85154
S406
L
F
N
E
L
D
R
S
V
V
K
E
H
P
P
Dog
Lupus familis
XP_540804
876
99392
R530
L
F
N
E
F
D
K
R
V
I
K
E
H
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWC0
731
83577
G390
L
F
D
E
V
D
K
G
L
A
K
E
R
P
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506335
738
85478
D392
I
F
D
E
L
D
K
D
A
V
K
E
H
P
P
Chicken
Gallus gallus
NP_001137403
752
87078
L364
L
K
I
R
S
H
P
L
G
Q
W
M
P
R
V
Frog
Xenopus laevis
NP_001089672
327
37780
V26
N
L
V
S
V
C
I
V
L
V
I
D
A
E
K
Zebra Danio
Brachydanio rerio
A0JMD4
774
89166
D422
L
F
N
E
L
D
K
D
F
V
K
E
H
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001138448
798
92257
T455
F
D
C
L
D
H
Q
T
D
E
D
E
I
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94KI8
733
84855
F388
F
K
I
N
K
D
E
F
A
D
L
C
Q
A
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
95.3
71.1
N.A.
72.8
N.A.
N.A.
69.5
28.1
29.2
54.6
N.A.
N.A.
N.A.
N.A.
42.4
Protein Similarity:
100
92.4
96.9
77
N.A.
84.7
N.A.
N.A.
82.3
48.9
36.2
72.2
N.A.
N.A.
N.A.
N.A.
60.4
P-Site Identity:
100
26.6
100
73.3
N.A.
46.6
N.A.
N.A.
66.6
6.6
6.6
80
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
46.6
100
86.6
N.A.
73.3
N.A.
N.A.
86.6
6.6
26.6
86.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
19
10
10
0
10
10
0
% A
% Cys:
0
0
10
0
0
10
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
10
19
0
10
64
0
19
10
10
10
10
0
0
0
% D
% Glu:
0
0
0
55
0
0
10
0
0
10
0
64
0
10
0
% E
% Phe:
19
55
0
10
10
0
0
10
19
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
19
0
0
0
0
0
0
55
0
0
% H
% Ile:
10
0
28
0
0
0
10
0
0
10
10
0
10
0
10
% I
% Lys:
0
19
0
0
10
0
37
0
0
0
55
0
0
0
10
% K
% Leu:
55
10
0
10
37
0
0
10
19
10
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
19
0
37
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
10
73
55
% P
% Gln:
0
0
0
0
0
0
10
0
0
10
0
10
10
0
0
% Q
% Arg:
0
0
0
10
0
0
28
10
0
0
0
0
10
10
0
% R
% Ser:
0
0
0
10
10
10
0
19
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
19
0
0
19
28
46
0
0
0
0
10
% V
% Trp:
0
10
0
0
10
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _